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Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction

Endothelial cell (EC) dysfunction is associated with many disease states including deep vein thrombosis (DVT), chronic kidney disease, sepsis and diabetes. Loss of the glycocalyx, a thin glycosaminoglycan (GAG)-rich layer on the EC surface, is a key feature of endothelial dysfunction and increases e...

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Dades bibliogràfiques
Publicat a:Pharmaceuticals (Basel)
Autors principals: Wodicka, James R., Chambers, Andrea M., Sangha, Gurneet S., Goergen, Craig J., Panitch, Alyssa
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490393/
https://ncbi.nlm.nih.gov/pubmed/28353658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10020036
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