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Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction

Endothelial cell (EC) dysfunction is associated with many disease states including deep vein thrombosis (DVT), chronic kidney disease, sepsis and diabetes. Loss of the glycocalyx, a thin glycosaminoglycan (GAG)-rich layer on the EC surface, is a key feature of endothelial dysfunction and increases e...

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Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Wodicka, James R., Chambers, Andrea M., Sangha, Gurneet S., Goergen, Craig J., Panitch, Alyssa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490393/
https://ncbi.nlm.nih.gov/pubmed/28353658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10020036
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