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Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction

Endothelial cell (EC) dysfunction is associated with many disease states including deep vein thrombosis (DVT), chronic kidney disease, sepsis and diabetes. Loss of the glycocalyx, a thin glycosaminoglycan (GAG)-rich layer on the EC surface, is a key feature of endothelial dysfunction and increases e...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Wodicka, James R., Chambers, Andrea M., Sangha, Gurneet S., Goergen, Craig J., Panitch, Alyssa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490393/
https://ncbi.nlm.nih.gov/pubmed/28353658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10020036
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