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LC-0882 targets PAK4 and inhibits PAK4-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells

Gastric cancer is the most common malignant tumor and globally the third leading cause of cancer-related deaths. Therefore, there exists an urgent need to identify new effective gastric cancer treatments. Given the important roles in tumorigenesis and progression, p21-activated kinase 4 (PAK4) has b...

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I publikationen:Am J Transl Res
Huvudupphovsmän: Zhang, Hong-Yan, Zhang, Jian, Hao, Chen-Zhou, Zhou, Ying, Wang, Jian, Cheng, Mao-Sheng, Zhao, Dong-Mei, Li, Feng
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489877/
https://ncbi.nlm.nih.gov/pubmed/28670365
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