Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression

Targeted gene modification mediated by single-stranded oligonucleotides (SSOs) holds great potential for widespread use in a number of biological and biomedical fields, including functional genomics and gene therapy. By using this approach, specific genetic changes have been created in a number of p...

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Detalhes bibliográficos
Main Authors: Wu, Xue-Song, Xin, Li, Yin, Wen-Xuan, Shang, Xi-Ying, Lu, Lu, Watt, Rory M., Cheah, Kathryn S. E., Huang, Jian-Dong, Liu, De-Pei, Liang, Chih-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548982/
https://ncbi.nlm.nih.gov/pubmed/15695590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406991102
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