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Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies
Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low. A major reason for this is the limited entry of the toxin into the cytosol of the target cell, which is required to mediat...
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Publicado no: | Biomedicines |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5489800/ https://ncbi.nlm.nih.gov/pubmed/28536357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines5020014 |
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