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Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies

Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low. A major reason for this is the limited entry of the toxin into the cytosol of the target cell, which is required to mediat...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Fuchs, Hendrik, Niesler, Nicole, Trautner, Alexandra, Sama, Simko, Jerz, Gerold, Panjideh, Hossein, Weng, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489800/
https://ncbi.nlm.nih.gov/pubmed/28536357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines5020014
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