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A universal plasmid library encoding all permutations of small interfering RNA

Small interfering RNA (siRNA) is normally designed to silence preselected known genes. Such selections are inevitably prone to bias as a result of limited knowledge about the biological process, transcript identity, and functions. A library that contains all permutations of siRNA could avoid such pr...

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Hlavní autoři: Chen, Meihong, Zhang, Lishu, Zhang, Hong-Yan, Xiong, Xiahui, Wang, Bo, Du, Quan, Lu, Bing, Wahlestedt, Claes, Liang, Zicai
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC548965/
https://ncbi.nlm.nih.gov/pubmed/15695593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401549101
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