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A universal plasmid library encoding all permutations of small interfering RNA
Small interfering RNA (siRNA) is normally designed to silence preselected known genes. Such selections are inevitably prone to bias as a result of limited knowledge about the biological process, transcript identity, and functions. A library that contains all permutations of siRNA could avoid such pr...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548965/ https://ncbi.nlm.nih.gov/pubmed/15695593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401549101 |
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