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NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors

Yes-associated protein (YAP) is a downstream target of the Hippo pathway and has been found to be oncogenic driving many cancers into developing metastatic phenotypes leading to poor survival outcomes. This study investigated if YAP expression is associated with drug resistance in two non-small cell...

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Detalles Bibliográficos
Publicado en:Genes Cancer
Main Authors: McGowan, Marc, Kleinberg, Lilach, Halvorsen, Ann Rita, Helland, Åslaug, Brustugun, Odd Terje
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489647/
https://ncbi.nlm.nih.gov/pubmed/28680534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.136
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