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NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors

Yes-associated protein (YAP) is a downstream target of the Hippo pathway and has been found to be oncogenic driving many cancers into developing metastatic phenotypes leading to poor survival outcomes. This study investigated if YAP expression is associated with drug resistance in two non-small cell...

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Publicado en:Genes Cancer
Autores principales: McGowan, Marc, Kleinberg, Lilach, Halvorsen, Ann Rita, Helland, Åslaug, Brustugun, Odd Terje
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489647/
https://ncbi.nlm.nih.gov/pubmed/28680534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.136
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