Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand

Nitroalkene derivatives of linoleic acid (nitrolinoleic acid, LNO(2)) are formed via nitric oxide-dependent oxidative inflammatory reactions and are found at concentrations of ≈500 nM in the blood of healthy individuals. We report that LNO(2) is a potent endogenous ligand for peroxisome proliferator...

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Main Authors: Schopfer, Francisco J., Lin, Yiming, Baker, Paul R. S., Cui, Taixing, Garcia-Barrio, Minerva, Zhang, Jifeng, Chen, Kai, Chen, Yuqing E., Freeman, Bruce A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC548962/
https://ncbi.nlm.nih.gov/pubmed/15701701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408384102
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