The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo

Glucagon like peptide-1 (GLP-1) plays a vital role in glucose homeostasis and sustaining β-cell function. Currently there are two major methods to enhance endogenous GLP-1 activity; inhibiting dipeptidyl peptidase-4 (DPP4) or activating G protein-coupled receptor 119 (GPR119). Here we describe and v...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Huan, Yi, Jiang, Qian, Li, Gang, Bai, Guoliang, Zhou, Tian, Liu, Shuainan, Li, Caina, Liu, Quan, Sun, Sujuan, Yang, Miaomiao, Guo, Nan, Wang, Xing, Wang, Shusen, Liu, Yaojuan, Wang, Guanqiao, Huang, Haihong, Shen, Zhufang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489512/
https://ncbi.nlm.nih.gov/pubmed/28659588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04633-5
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items