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Chemical and structural biology of protein lysine deacetylases

Histone acetylation is a reversible posttranslational modification that plays a fundamental role in regulating eukaryotic gene expression and chromatin structure/function. Key enzymes for removing acetyl groups from histones are metal (zinc)-dependent and NAD(+)-dependent histone deacetylases (HDACs...

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Detalhes bibliográficos
Publicado no:Proc Jpn Acad Ser B Phys Biol Sci
Main Authors: YOSHIDA, Minoru, KUDO, Norio, KOSONO, Saori, ITO, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Academy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489435/
https://ncbi.nlm.nih.gov/pubmed/28496053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.93.019
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