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Purinergic signaling in microglia in the pathogenesis of neuropathic pain

Nerve injury often causes debilitating chronic pain, referred to as neuropathic pain, which is refractory to currently available analgesics including morphine. Many reports indicate that activated spinal microglia evoke neuropathic pain. The P2X4 receptor (P2X4R), a subtype of ionotropic ATP recepto...

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Bibliografske podrobnosti
izdano v:Proc Jpn Acad Ser B Phys Biol Sci
Glavni avtor: INOUE, Kazuhide
Format: Artigo
Jezik:Inglês
Izdano: The Japan Academy 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489427/
https://ncbi.nlm.nih.gov/pubmed/28413195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.93.011
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