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Microglia-neuronal signalling in neuropathic pain hypersensitivity 2.0

Microglia are increasingly recognized as critical in the pathogenesis of pain hypersensitivity caused by injury to peripheral nerves. The core signalling pathway is through P2X4 purinergic receptors on the microglia which, via the release brain derived neurotrophic factor, cause disinhibition of noc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beggs, Simon, Salter, Michael W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589562/
https://ncbi.nlm.nih.gov/pubmed/20817512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2010.08.005
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