Structural mechanism of ATP-independent transcription initiation by RNA polymerase I

Transcription initiation by RNA Polymerase I (Pol I) depends on the Core Factor (CF) complex to recognize the upstream promoter and assemble into a Pre-Initiation Complex (PIC). Here, we solve a structure of Saccharomyces cerevisiae Pol I-CF-DNA to 3.8 Å resolution using single-particle cryo-electro...

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Veröffentlicht in:eLife
Hauptverfasser: Han, Yan, Yan, Chunli, Nguyen, Thi Hoang Duong, Jackobel, Ashleigh J, Ivanov, Ivaylo, Knutson, Bruce A, He, Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Biophysics and Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489313/
https://ncbi.nlm.nih.gov/pubmed/28623663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27414
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