Phase I clinical trial of idiotypic DNA vaccine administered as a complex with polyethylenimine to patients with B-cell lymphoma

We report on the design of a phase I, non-randomized, open-label study of idiotypic DNA vaccination in patients with B-cell non-Hodgkin's lymphoma (ISRCTN31090206). The study uses DNA fusion gene vaccination encoding patient-specific single chain variable fragment, or idiotype, linked to an imm...

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Bibliografski detalji
Izdano u:Hum Vaccin Immunother
Glavni autori: Meleshko, A. N., Petrovskaya, N. A., Savelyeva, N., Vashkevich, K. P., Doronina, S. N., Sachivko, N. V.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Commentary
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489279/
https://ncbi.nlm.nih.gov/pubmed/28272989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1285477
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