Active Idiotypic Vaccination Versus Control Immunotherapy for Follicular Lymphoma

PURPOSE: Idiotypes (Ids), the unique portions of tumor immunoglobulins, can serve as targets for passive and active immunotherapies for lymphoma. We performed a multicenter, randomized trial comparing a specific vaccine (MyVax), comprising Id chemically coupled to keyhole limpet hemocyanin (KLH) plu...

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Hlavní autoři: Levy, Ronald, Ganjoo, Kristen N., Leonard, John P., Vose, Julie M., Flinn, Ian W., Ambinder, Richard F., Connors, Joseph M., Berinstein, Neil L., Belch, Andrew R., Bartlett, Nancy L., Nichols, Craig, Emmanouilides, Christos E., Timmerman, John M., Gregory, Stephanie A., Link, Brian K., Inwards, David J., Freedman, Arnold S., Matous, Jeffrey V., Robertson, Michael J., Kunkel, Lori A., Ingolia, Diane E., Gentles, Andrew J., Liu, Chih Long, Tibshirani, Robert, Alizadeh, Ash A., Denney, Dan W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2014
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039868/
https://ncbi.nlm.nih.gov/pubmed/24799467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.43.9273
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