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Endothelin-induced increases in vascular smooth muscle Ca2+ do not depend on dihydropyridine-sensitive Ca2+ channels.

Endothelin is a potent mammalian vasoconstrictive peptide with structural homology to cation channel-binding insect toxins. We tested the proposal that this peptide directly activates dihydropyridine-sensitive Ca2+ channels in cultured vascular smooth muscle (VSM) cells. First, we found that cell Ca...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mitsuhashi, T, Morris, R C, Ives, H E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548926/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547835/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114209
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