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Comparison of X-chromosome inactivation patterns in multiple tissues from human females

BACKGROUND: X-chromosome inactivation (XCI) is the mechanism by which gene dosage uniformity is achieved between female mammals with two X chromosomes and male mammals with a single X chromosome, and is thought to occur randomly. For molecular genetic testing, accessible tissues (eg blood) are commo...

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Bibliografische gegevens
Gepubliceerd in:J Med Genet
Hoofdauteurs: Bittel, D C, Theodoro, M F, Kibiryeva, N, Fischer, W, Talebizadeh, Z, Butler, M G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489244/
https://ncbi.nlm.nih.gov/pubmed/18156436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.055244
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