Conditional knock-out of lipoic acid protein ligase 1 reveals redundancy pathway for lipoic acid metabolism in Plasmodium berghei malaria parasite

BACKGROUND: Lipoic acid is a cofactor for α-keto acid dehydrogenase system that is involved in the central energy metabolism. In the apicomplexan parasite, Plasmodium, lipoic acid protein ligase 1 (LplA1) and LplA2 catalyse the ligation of acquired lipoic acid to the dehydrogenase complexes in the m...

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Bibliografiske detaljer
Udgivet i:Parasit Vectors
Main Authors: Wang, Min, Wang, Qiong, Gao, Xiang, Su, Zhong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488443/
https://ncbi.nlm.nih.gov/pubmed/28655332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-2253-y
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