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Artesunate ameliorates lung fibrosis via inhibiting the Notch signaling pathway

The present study aimed to determine the underlying molecular mechanism of the antifibrotic effect of artesunate in pulmonary fibrosis (PF). Primary lung fibroblasts were isolated from the lung tissues of rats, and treated with artesunate (8 µg/ml) and transforming growth factor (TGF)-β1 (5 ng/ml)....

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Liu, Yujuan, Huang, Guojin, Mo, Biwen, Wang, Changming
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488411/
https://ncbi.nlm.nih.gov/pubmed/28672967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4573
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