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LPS enhances TLR4 expression and IFN-γ production via the TLR4/IRAK/NF-κB signaling pathway in rat pulmonary arterial smooth muscle cells

The aim of the present study was to investigate the role of the Toll-like receptor (TLR)4 signaling pathway in cellular response to lipopolysaccharide (LPS) in rat pulmonary artery smooth muscle cells (PASMCs). Chronic obstructive pulmonary disease (COPD) rats were established with passive inhaling...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Wang, Pengyan, Han, Xuhui, Mo, Biwen, Huang, Guojin, Wang, Changming
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547977/
https://ncbi.nlm.nih.gov/pubmed/28714001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6983
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