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Overexpression of the X-Linked Inhibitor of Apoptosis Protects Against Retinal Degeneration in a Feline Model of Retinal Detachment

Retinal detachment is an acute disorder in humans that is caused by trauma or disease, and it can often lead to permanent visual deficits that result from the death of photoreceptors in the retina. The final pathway for photoreceptor cell death is apoptosis and necroptosis. The X-linked inhibitor of...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Gene Ther
Hauptverfasser: Wassmer, Sarah J., Leonard, Brian C., Coupland, Stuart G., Baker, Adam N., Hamilton, John, Hauswirth, William W., Tsilfidis, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488383/
https://ncbi.nlm.nih.gov/pubmed/28335619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.161
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