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Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection

Vectors based on the adeno-associated virus (AAV) are currently the preferred tools for delivering genes to photoreceptors (PR) in small and large animals. AAVs have been applied successfully in various models of PR dystrophies. However, unknown barriers still limit AAV's efficient application...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Hum Gene Ther
Autori principali: Petit, Lolita, Ma, Shan, Cheng, Shun-Yun, Gao, Guangping, Punzo, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488363/
https://ncbi.nlm.nih.gov/pubmed/28510482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.020
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