Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection

Vectors based on the adeno-associated virus (AAV) are currently the preferred tools for delivering genes to photoreceptors (PR) in small and large animals. AAVs have been applied successfully in various models of PR dystrophies. However, unknown barriers still limit AAV's efficient application...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Gene Ther
Prif Awduron: Petit, Lolita, Ma, Shan, Cheng, Shun-Yun, Gao, Guangping, Punzo, Claudio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488363/
https://ncbi.nlm.nih.gov/pubmed/28510482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.020
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