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Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection

Vectors based on the adeno-associated virus (AAV) are currently the preferred tools for delivering genes to photoreceptors (PR) in small and large animals. AAVs have been applied successfully in various models of PR dystrophies. However, unknown barriers still limit AAV's efficient application...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Petit, Lolita, Ma, Shan, Cheng, Shun-Yun, Gao, Guangping, Punzo, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488363/
https://ncbi.nlm.nih.gov/pubmed/28510482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.020
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