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Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress

Neuroinflammation is considered as one of the common pathogeneses of depression. Huanglian-Jie-Du-Tang (HJDT) is a traditional Chinese herbal formula. The present study investigates the antidepressant-like effect of HJDT and its possible mechanism in rats. Rats were given HJDT (2, 4, and 8 g/kg, int...

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Dades bibliogràfiques
Publicat a:Evid Based Complement Alternat Med
Autors principals: Ye, Yi-Lu, Zhong, Kai, Liu, Dan-Dan, Xu, Jing, Pan, Bei-Bei, Li, Xiang, Yu, Yue-Ping, Zhang, Qi
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488320/
https://ncbi.nlm.nih.gov/pubmed/28694833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7903918
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