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Estrogen administration attenuates post-stroke depression by enhancing CREB/BDNF/TrkB signaling in the rat hippocampus

A previous study demonstrated that 17β-estradiol (E2), which is an antidepressant, can ameliorate post-stroke depression (PSD); however, the underlying mechanisms governing this remain largely unknown. Therefore, the present study developed a PSD model in rats, which was induced by left middle cereb...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: Jiang, Huigang, Xiao, Li, Jin, Kunlin, Shao, Bei
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967838/
https://ncbi.nlm.nih.gov/pubmed/33747172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.9850
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