Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma

SND1, a subunit of the miRNA regulatory complex RISC, has been implicated as an oncogene in hepatocellular carcinoma (HCC). In this study, we show that hepatocyte-specific SND1 transgenic mice (Alb/SND1 mice) develop spontaneous HCC with partial penetrance and exhibit more highly aggressive HCC indu...

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Udgivet i:Cancer Res
Main Authors: Jariwala, Nidhi, Rajasekaran, Devaraja, Mendoza, Rachel G., Shen, Xue-Ning, Siddiq, Ayesha, Akiel, Maaged A., Robertson, Chadia L., Subler, Mark A., Windle, Jolene J., Fisher, Paul B., Sanyal, Arun J., Sarkar, Devanand
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488274/
https://ncbi.nlm.nih.gov/pubmed/28428278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0298
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