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A New Methodology for Incorporating Chiral Linkers into Stapled Peptides
Stapled peptides have arisen as a new class of chemical probe and potential therapeutic agents for modulating protein–protein interactions. Here, we report the first two‐component i,i+7 stapling methodology that makes use of two orthogonal, on‐resin stapling reactions to incorporate linkers bearing...
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| Udgivet i: | Chembiochem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488175/ https://ncbi.nlm.nih.gov/pubmed/28388005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700075 |
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