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Two Saporin-Containing Immunotoxins Specific for CD20 and CD22 Show Different Behavior in Killing Lymphoma Cells

Immunotoxins (ITs) are hybrid proteins combining the binding specificity of antibodies with the cytocidal properties of toxins. They represent a promising approach to lymphoma therapy. The cytotoxicity of two immunotoxins obtained by chemical conjugation of the plant toxin saporin-S6 with the anti-C...

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Dettagli Bibliografici
Pubblicato in:Toxins (Basel)
Autori principali: Polito, Letizia, Mercatelli, Daniele, Bortolotti, Massimo, Maiello, Stefania, Djemil, Alice, Battelli, Maria Giulia, Bolognesi, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488032/
https://ncbi.nlm.nih.gov/pubmed/28556822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9060182
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