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Two Saporin-Containing Immunotoxins Specific for CD20 and CD22 Show Different Behavior in Killing Lymphoma Cells

Immunotoxins (ITs) are hybrid proteins combining the binding specificity of antibodies with the cytocidal properties of toxins. They represent a promising approach to lymphoma therapy. The cytotoxicity of two immunotoxins obtained by chemical conjugation of the plant toxin saporin-S6 with the anti-C...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Polito, Letizia, Mercatelli, Daniele, Bortolotti, Massimo, Maiello, Stefania, Djemil, Alice, Battelli, Maria Giulia, Bolognesi, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488032/
https://ncbi.nlm.nih.gov/pubmed/28556822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9060182
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