Sample Preparation Strategies for the Effective Quantitation of Hydrophilic Metabolites in Serum by Multi-Targeted HILIC-MS/MS

The effect of endogenous interferences of serum in multi-targeted metabolite profiling HILIC-MS/MS analysis was investigated by studying different sample preparation procedures. A modified QuEChERS dispersive SPE protocol, a HybridSPE protocol, and a combination of liquid extraction with protein pre...

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Bibliografiske detaljer
Udgivet i:Metabolites
Main Authors: Tsakelidou, Elisavet, Virgiliou, Christina, Valianou, Lemonia, Gika, Helen G., Raikos, Nikolaos, Theodoridis, Georgios
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487984/
https://ncbi.nlm.nih.gov/pubmed/28358315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo7020013
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