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S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion

DNA replication stress, an important source of genomic instability, arises upon different types of DNA replication perturbations, including those that stall replication fork progression. Inhibitors of the cellular pool of deoxynucleotide triphosphates (dNTPs) slow down DNA synthesis throughout the g...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Giannattasio, Michele, Branzei, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487892/
https://ncbi.nlm.nih.gov/pubmed/28220209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2474-4
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