Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity

Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying transcription activators that drive the transcriptional response to amino acid limitation. The cpc-1 mRNA contains two upstream open reading frames (uORFs) in its >700-nucleotide (nt) 5′ leader, and its expression i...

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Vydáno v:mBio
Hlavní autoři: Ivanov, Ivaylo P., Wei, Jiajie, Caster, Stephen Z., Smith, Kristina M., Michel, Audrey M., Zhang, Ying, Firth, Andrew E., Freitag, Michael, Dunlap, Jay C., Bell-Pedersen, Deborah, Atkins, John F., Sachs, Matthew S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487733/
https://ncbi.nlm.nih.gov/pubmed/28655822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00844-17
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