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MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes.

Shortly after their birth, postmitotic mononucleated myoblasts in myotomes, limb buds, and conventional muscle cultures elongate and assemble a cohort of myofibrillar proteins into definitively striated myofibrils. MyoD induces a number of immortalized and/or transformed nonmuscle cells to express d...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Choi, J, Costa, M L, Mermelstein, C S, Chagas, C, Holtzer, S, Holtzer, H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.20.7988
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