Safety, Pharmacokinetics, and Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment-Naive HIV-Infected Subjects in a Phase 2 Randomized, Controlled Study

We investigated the safety and antiviral effects of an anti-HIV compound (ABX464) with a unique mechanism of viral replication inhibition. This was a randomized, double-blind, placebo-controlled, dose-ranging study in treatment-naive HIV-infected patients. Participants were assigned to eight groups;...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Steens, Jean-Marc, Scherrer, Didier, Gineste, Paul, Barrett, P. Noel, Khuanchai, Supparatpino, Winai, Ratanasuwan, Ruxrungtham, Kiat, Tazi, Jamal, Murphy, Robert, Ehrlich, Hartmut
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487684/
https://ncbi.nlm.nih.gov/pubmed/28507108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00545-17
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