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Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor

Hand-foot-and-mouth disease (HFMD), caused by enterovirus, is a threat to public health worldwide. To date, enterovirus 71 (EV71) has been one of the major causative agents of HFMD in the Pacific-Asia region, and outbreaks with EV71 cause millions of infections. However, no drug is currently availab...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Wang, Yaxin, Cao, Lin, Zhai, Yangyang, Yin, Zheng, Sun, Yuna, Shang, Luqing
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487676/
https://ncbi.nlm.nih.gov/pubmed/28461310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00298-17
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