Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene

Terbinafine is one of the allylamine antifungal agents whose target is squalene epoxidase (SQLE). This agent has been extensively used in the therapy of dermatophyte infections. The incidence of patients with tinea pedis or unguium tolerant to terbinafine treatment prompted us to screen the terbinaf...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Yamada, Tsuyoshi, Maeda, Mari, Alshahni, Mohamed Mahdi, Tanaka, Reiko, Yaguchi, Takashi, Bontems, Olympia, Salamin, Karine, Fratti, Marina, Monod, Michel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487658/
https://ncbi.nlm.nih.gov/pubmed/28416557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00115-17
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