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Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen: Replicating and Shielding Viral DNA during Viral Persistence

Kaposi's sarcoma herpesvirus (KSHV) establishes lifelong latency. The viral latency-associated nuclear antigen (LANA) promotes viral persistence by tethering the viral genome to cellular chromosomes and by participating in latent DNA replication. Recently, the structure of the LANA C-terminal D...

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Udgivet i:J Virol
Main Authors: Weidner-Glunde, Magdalena, Mariggiò, Giuseppe, Schulz, Thomas F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Gem
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487577/
https://ncbi.nlm.nih.gov/pubmed/28446671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01083-16
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