Rubicon Modulates Antiviral Type I Interferon (IFN) Signaling by Targeting IFN Regulatory Factor 3 Dimerization

Rubicon is part of a Beclin-1-Vps34-containing autophagy complex. Rubicon induces antimicrobial responses upon Toll-like receptor (TLR) stimulation and functions as a feedback inhibitor to prevent unbalanced proinflammatory responses depending on dectin-1 signaling. However, the role played by Rubic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kim, Jae-Hoon, Kim, Tae-Hwan, Lee, Hyun-Cheol, Nikapitiya, Chamilani, Uddin, Md Bashir, Park, Min-Eun, Pathinayake, Prabuddha, Lee, Eun Seo, Chathuranga, Kiramage, Herath, Thilina U. B., Chathuranga, W. A. Gayan, Lee, Jong-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487567/
https://ncbi.nlm.nih.gov/pubmed/28468885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00248-17
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