Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration

Human herpesviruses 6A and 6B (HHV-6A/B) can integrate their genomes into the telomeres of human chromosomes using a mechanism that remains poorly understood. To achieve a better understanding of the HHV-6A/B integration mechanism, we made use of BRACO-19, a compound that stabilizes G-quadruplex sec...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Gilbert-Girard, Shella, Gravel, Annie, Artusi, Sara, Richter, Sara N., Wallaschek, Nina, Kaufer, Benedikt B., Flamand, Louis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487558/
https://ncbi.nlm.nih.gov/pubmed/28468887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00402-17
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