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The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres

Human herpesvirus 6B (HHV-6B) is a betaherpesvirus capable of integrating its genome into the telomeres of host chromosomes. Until now, the cellular and/or viral proteins facilitating HHV-6B integration have remained elusive. Here we show that a cellular protein, the promyelocytic leukemia protein (...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Collin, Vanessa, Gravel, Annie, Kaufer, Benedikt B., Flamand, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394443/
https://ncbi.nlm.nih.gov/pubmed/32658923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008683
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