Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways

AIM: To study the molecular mechanisms involved in the hepatoprotective effects of naringenin (NAR) on carbon tetrachloride (CCl(4))-induced liver fibrosis. METHODS: Thirty-two male Wistar rats (120-150 g) were randomly divided into four groups: (1) a control group (n = 8) that received 0.7% carboxy...

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Enregistré dans:
Détails bibliographiques
Publié dans:World J Gastroenterol
Auteurs principaux: Hernández-Aquino, Erika, Zarco, Natanael, Casas-Grajales, Sael, Ramos-Tovar, Erika, Flores-Beltrán, Rosa E, Arauz, Jonathan, Shibayama, Mineko, Favari, Liliana, Tsutsumi, Víctor, Segovia, José, Muriel, Pablo
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2017
Sujets:
Basic Study
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487499/
https://ncbi.nlm.nih.gov/pubmed/28706418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i24.4354
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