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Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling

Mania causes symptoms of hyperactivity, impulsivity, elevated mood, reduced anxiety and decreased need for sleep, which suggests that the dysfunction of the striatum, a critical component of the brain motor and reward system, can be causally associated with mania. However, detailed molecular pathoph...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Lee, Yeunkum, Kim, Sun Gyun, Lee, Bokyoung, Zhang, Yinhua, Kim, Yoonhee, Kim, Shinhyun, Kim, Eunjoon, Kang, Hyojin, Han, Kihoon
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487420/
https://ncbi.nlm.nih.gov/pubmed/28701918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00201
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