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Coordination of Bactericidal and Iron Regulatory Functions of Hepcidin in Innate Antimicrobial Immunity in a Zebrafish Model

Hepcidin acts as both an antimicrobial peptide and a hormonal regulator of iron homeostasis; however, the biological significance of this dual-function in immune reactions remains elusive. In this study, we provide experimental evidence regarding the coordination of this dual-function in the innate...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jiang, Xiao-feng, Liu, Zhi-fei, Lin, Ai-fu, Xiang, Li-xin, Shao, Jian-zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487360/
https://ncbi.nlm.nih.gov/pubmed/28655927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04069-x
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