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Suppression of Iron-Regulatory Hepcidin by Vitamin D

The antibacterial protein hepcidin regulates the absorption, tissue distribution, and extracellular concentration of iron by suppressing ferroportin-mediated export of cellular iron. In CKD, elevated hepcidin and vitamin D deficiency are associated with anemia. Therefore, we explored a possible role...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bacchetta, Justine, Zaritsky, Joshua J., Sea, Jessica L., Chun, Rene F., Lisse, Thomas S., Zavala, Kathryn, Nayak, Anjali, Wesseling-Perry, Katherine, Westerman, Mark, Hollis, Bruce W., Salusky, Isidro B., Hewison, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935584/
https://ncbi.nlm.nih.gov/pubmed/24204002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013040355
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