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Systemic QSAR and phenotypic virtual screening: chasing butterflies in drug discovery

Current advances in systems biology suggest a new change of paradigm reinforcing the holistic nature of the drug discovery process. According to the principles of systems biology, a simple drug perturbing a network of targets can trigger complex reactions. Therefore, it is possible to connect initia...

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Detalhes bibliográficos
Publicado no:Drug Discov Today
Main Authors: Cruz-Monteagudo, Maykel, Schürer, Stephan, Tejera, Eduardo, Pérez-Castillo, Yunierkis, Medina-Franco, José L., Sánchez-Rodríguez, Aminael, Borges, Fernanda
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487293/
https://ncbi.nlm.nih.gov/pubmed/28274840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2017.02.004
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