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A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis

A conditional-lethal recombinant virus was constructed in which the expression of the vaccinia virus I7L gene is under the control of the tetracycline operator/repressor system. In the absence of I7L expression, processing of the major VV core proteins is inhibited and electron microscopy reveals de...

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Autors principals: Byrd, Chelsea M, Hruby, Dennis E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548685/
https://ncbi.nlm.nih.gov/pubmed/15701171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-4
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