Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia: the importance of characterizing ABL1 mutations in cerebrospinal fluid

We investigated the frequency, predictors, and evolution of acute lymphoblastic leukemia (ALL) in patients with CNS relapse and introduced a novel method for studying BCR-ABL1 protein variants in cDNA from bone marrow (BM) and cerebrospinal fluid (CSF) blast cells. A total of 128 patients were analy...

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Vydáno v:Ann Hematol
Hlavní autoři: Sanchez, Ricardo, Ayala, Rosa, Alonso, Rafael Alberto, Martínez, María Pilar, Ribera, Jordi, García, Olga, Sanchez-Pina, José, Mercadal, Santiago, Montesinos, Pau, Martino, Rodrigo, Barba, Pere, González-Campos, José, Barrios, Manuel, Lavilla, Esperanza, Gil, Cristina, Bernal, Teresa, Escoda, Lourdes, Abella, Eugenia, Amigo, Ma Luz, Moreno, Ma José, Bravo, Pilar, Guàrdia, Ramón, Hernández-Rivas, Jesús-María, García-Guiñón, Antoni, Piernas, Sonia, Ribera, José-María, Martínez-López, Joaquín
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486784/
https://ncbi.nlm.nih.gov/pubmed/28451802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-017-3002-1
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