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The loss of NKX3.1 expression in testicular – and prostate – cancers is not caused by promoter hypermethylation
BACKGROUND: Recent studies have demonstrated that the NKX3.1 protein is commonly down-regulated in testicular germ cell tumors (TGCTs) and prostate carcinomas. The homeobox gene NKX3.1 maps to chromosome band 8p21, which is a region frequently lost in prostate cancer, but not in TGCT. Mutations have...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548671/ https://ncbi.nlm.nih.gov/pubmed/15691383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-4-8 |
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